Explore 18 proven alternative cancer treatments and therapies that can help manage side effects and complement traditional care for people with cancer.
I just finished a 7-day fast. My longest is 14 days. My personal opinion is that if you have been able to complete 5 days without major complications AND you have the discipline to break your fast slowly over 1/2 the time you were fasting, then you can probably gradually increase on your own safely (500 cal is the limit for day 1 re-feeding - read-up on Refeeding Syndrome). 40 days is going to require a great deal of care in breaking the fast and if you gradually build-up to longer fasts, you might not have the fat reserves to do 40 days anyway - you lose 3/4 pound per day of fat.
Yes, I have phosphorus ready for re-feeding. Thanks for your input. I’ve learned how much sodium (and potassium and magnesium) that my body needs on a 5 day one. I’m aware of the need to add calcium, etc. after 14 days. Congrats on your 14 day fast. Was that your goal?
Yes. If you plan on going further than 14 days, I found that after 14 days I felt like I could go indefinitely and have OK energy - so that's something you can look forward to if you want to go for it. I think it starts to get slowly better after 7 days. For the 14 day fast I took vacation for the first 7 days and very light work for the next 7.
Would either of you be willing to share the best material you have on reading up on this? I feel I always encounter so much contradictory material (probably intentionally like with diet) that it becomes difficult to parse. So I’d like to really understand the mechanics and the differences between the different types and lengths.
(1 of 2) The most important single piece of nutrition advice is to supplement vitamin D3 to attain at least the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) level of 25-hydroxyvitamin D (as measured in "vitamin D" blood tests), which the immune system needs to function properly.
Links to and discussion of the most pertinent research on the three vitamin D compounds and the immune system are at: https://vitamindstopscovid.info/00-evi/. This begins with recommendations from New Jersey based Professor of Medicine Sunil Wimalawansa for how much vitamin D3 to supplement to attain this level safely, without the need for blood tests or medical monitoring. The amount depends on body weight and obesity status. For 70 kg 154lb body weight without obesity, 0.125 milligrams (125 micrograms = 5000 IU) a day is a good amount. These recommendations are based on his 2022 article in Nutrients: http:// www.mdpi.com/2072-6643/14/14/2997 as simplified somewhat in his FLCCC webinar: https:// odysee.com/@FrontlineCovid19CriticalCareAlliance:c/ Weeekly_Webinar_Aug16_2023:d?t=3386.
These supplemental intake quantities are 5 or more times those recommended by governments and many doctors, who are only aiming to attain the 20 ng/mL (50 nmol/L) level of circulating 25-hydroxyvitamin which the kidneys need to perform their role in the regulation of calcium-phosphate-bone metabolism.
The fuller version of this article: https://covid19criticalcare.com/alternative-cancer-treatments-interventions/ states this, and nominates 55 to 90 ng/mL (137 to 225 nmol/L) circulating 25-hydroxyvitamin D as the target range. This is healthy for the vast majority of people, who without proper vitamin D3 supplementation, or substantial ultraviolet-B radiation of ideally white skin, typically have levels between 5 and 25 ng/mL.
The research literature indicates that 25-hydroxyvitamin D levels up to 375 nmol/L (150 ng/mL) do not lead to hypercalcemia - an excessive level of calcium ions in the bloodstream, with reduced calcium in the bone. (Endocrine Society Clinical Practice Guideline 2011: https://doi.org/10.1210/jc.2011-0385 and McCullough et al. 2019: https://sci-hub.se/10.1016/j.jsbmb.2018.12.010.)
However, there is a report that some people suffer ill effects with 25-hydroxyvitamin D levels such as 197 nmol/L (79 ng/mL), such as after several years of supplementing what for most average weight adults is a perfectly healthy amount of vitamin D3 - 125 micrograms (5000 IU) a day: https://www.devaboone.com/ post/vitamin-d-part-2-shannon-s-story. These must be quite rare, since I have not seen such an account in the peer-reviewed literature.
Compared to the current situation of almost ubiquitous, unsupplemented, levels of 25-hydroxyvitamin D being a fraction of what the immune system needs to function properly, if everyone attained at least 50 ng/mL, there would be far less incidence of cancer or infectious diseases caused by bacteria and viruses. In the case of infectious diseases, such as COVID-19, influenza etc. fully functioning immune systems not only reduce the chance of severe symptoms, but reduce the number of bacteria or virus particles shed, which greatly reduces the rate at which the disease can be transmitted through a population.
The first compound, vitamin D3 cholecalciferol is for most practical purposes a vitamin. While we can produce it from UV-B skin exposure, most people cannot access the required amount of UV-B except from high elevation direct sunshine (without intervening glass, clothing or sunscreen) on cloud-free summer days, or at any time of the year except monsoon in equatorial regions. UV-B skin exposure damages DNA and so raises the risk of skin cancer. Furthermore, it has been proposed https://journals.physiology.org/doi/full/10.1152/ajpregu.00136.2019 that UV-B exposure degrades folate. This means that ingesting vitamin D3 is essential for most people to be healthy, making it a vitamin.
The second compound, 25-hydroxyvitamin D calcifediol (also: "calcidiol") is made primarily in the liver by hydroxylating vitamin D3 at the 25th carbon. About 1/4 of ingested or skin-produced vitamin D3 goes into circulation as 25-hydroxyvitamin D, where it has a half life of weeks to months (after long-term vitamin D3 supplementation).
Neither vitamin D3 nor 25-hydroxyvitamin D function as hormones. They are not signaling molecules. A hormone is a long-distance blood-borne signalling molecule: it is made somewhere in the body and goes into circulation in the bloodstream (and potentially the cerebrospinal fluid) where its level (concentration) affects or controls the behaviour of cells of one or more types in all parts of the body.
As Reinhold Vieth pointed out, referring to vitamin D3 as a hormone is not only incorrect, but will make many people overly wary of supplementing this vital nutrient. This is especially so when the small amounts required on average per day, (125 micrograms, totalling a gram every 22 years) are referred to with such large numbers as "5000 International Units".
The third compound is 1,25-dihydroxyvitamin D calcitriol, made from 25-hydroxyvitamin D by hydroxylating it (replacing a hydrogen with an oxygen-hydrogen hydroxyl group) on the number 1 carbon. Calcitriol has one well known hormonal function, so many people consider it to be a hormone. They are not aware that it also has many non-hormonal functions. As part of a feedback network involving the parathyroid gland and osteocyte bone cells, the kidneys maintain a very low (ca. 0.05 ng/mL), generally stable, level of circulating calcitriol, which acts as a long-distance blood-borne (endocrine) signaling molecule, hormonally affecting several types of cell which are involved in calcium and phosphate absorption and excretion, and bone maintenance.
Although structurally related, these three compounds have entirely different roles in the body, so it is a mistake to refer to them all as "vitamin D".
The immune system is not significantly affected by this very low, stable, level of circulating, hormonal calcitriol. Many types of immune cell rely on a good circulating level of 25-hydroxyvitamin D to supply their intracrine (inside each cell) and paracrine (to nearby cells of different types) signalling systems, which are crucial to each cell's ability to respond to its changing circumstances. These two signaling systems have never been explained in a tutorial fashion in the peer-reviewed literature. For such an explanation, see: https://vitamindstopscovid.info/00-evi/#02-compounds or in greater detail: https://vitamindstopscovid.info/02-intracrine/.
You might want to study the mechanism of ClO2 (remember, the much maligned "bleach"). It may have application as a pro-oxidant the immune system uses to attack cancer as well as many other diseases.
Dr. Paul Marik has a unique talent for coming up with alternative treatments for disease by using common pharmaceuticals (vitamins/supplements) and drugs that are produced for different ailments. I think the combination of Ivermectin and Fenbendazole is particularly effective as a cancer treatment.
If anyone knows if fasting truly works as an alternative to chemo please fill me in. My fiance, who is only 33 has metastatic breast cancer in her bones and now beginning in her lungs. We will try anything. Thanks.
Dr. Bryan Ardis, in his book released the last week in September of 2024, "Moving Beyond the COVID-19 Lies: Restoring Health & Hope For Humanity", fully documents that Snake Venom (from the King Cobra snake, the Chinese Krait snake, and others) was put into all the C-19 vaccines.
He also documents how Snake Venom causes miscarriages, infertility, turbo cancers, myocarditis, sudden death, heart attacks, blood clotting, Long Covid, mental health issues, and more.
Additionally, he cites a Harvard Study showing we all were lied to about Nicotine which is Not addictive. The addictive element in tobacco are the pyrazine chemicals. Nicotine is found in eggplant, potatoes, and more.
Wearing a Nicotine patch of 2 mg of 3 mg will eject the snake venom from the nicotinic receptor sites in the body where it 'lands' which will then get flushed out when using the restroom. Very few smokers got COVID-19 during the pandemic because of the nicotine found in the tobacco plant (to which pyrazines are added).
He also documents how wearing a Nicotine patch resolves all Long COVID issues.
At this late hour I can't locate in his book what he said nicotine did to turbo cancers except I remember it described a person with brain cancer whose tumor was reduced by 72% (or some huge figure like that) by using "the nutrient" nicotine.
Amazon sold out of his book on October 10th, I believe, and remains sold out. But you can order his book at www.thedrardisshow.com.
While you are there, watch his video on the first page, "The Explosive Truth, Origin, & Antidote for C-19". You will be nothing short of astounded.
Likewise for his 3-hour video on nicotine called "The Other N-Word-- the Complete 3 Hour Nicotine Expose". Lastly, his "Resources" section has plenty of information on nicotine and everything else.
This is Not a post advocating solely for Nicotine because his book lists many, and I do mean MANY remedies found in Nature for C-19 symptoms: Vitamin C, Glutathione, EDTA, and many more too numerous to list here. The last fourth of his book will put all his remedies from Nature in context in relation to specific symptoms.
So not only is Dr. Ardis's book solidly researched and documented, it also lists solutions for every COVID-19 issue.
Lastly, in one of his talks, he said Ozempic and Wegovy have snake venom in them. He also said to go to www.made-in-china.com and type in "snake venom peptides" into the search engine. When you do that, THOUSANDS of womens' cosmetics will come up each of which has some type of snake venom in them. Snake venom causes cancer and much more as listed above.
I can't do all his findings justice in this brief post. I encourage you to consider ordering the book. Keep up the great work you all do at FLCCC!
I've heard of folks having success with adjunctive supportive therapies like taking apricot kernel seeds, essiac tea, green tea, grape skins, a diet rich in cruciferous vegetables and mistletoe injections.
(2 of 2) There is very little vitamin D3 in food, including food which has been supplemented with vitamin D (often with the less effective vitamin D2). UV-B skin exposure can produce sufficient vitamin D3 to meet the needs of the immune system, but this is neither a practical nor safe way of attaining most of the vitamin D3 we need, year after year, due to sufficient UV-B light being generally unavailable and due to it damaging the skin, raising the risk of skin cancer and, as mentioned in my first comment, depleting folate.
So proper vitamin D3 supplementation, along the lines recommended by Prof. Wimalawansa (see previous comment, and some FLCCC protocols including MATH+) is essential for human health.
I suggest that the FLCCC develop a Vitamin D3 supplementation Protocol, to which all other protocols would refer.
This would begin with Prof. Wimalawansa's recommendations for long-term vitamin D3 supplementation, but also include his recommendations for using a single oral dose of 0.014 milligrams of calcifediol (which *is* 25-hydroxyvitamin D) per kilogram body weight (so 1 milligram for average weight adults) to boost the patient's 25-hydroxyvitamin D level from typical unsupplemented levels of 25 ng/mL or less, safely over 50 ng/mL, in 4 hours. This is also in the MATH+ protocol, along with a loading dose of ca. 10 mg (400,000 IU) vitamin D3, which takes about 4 days, due to the delays inherent in hydroxylation in the liver.
I suggest the protocol refer to the three (broadly) "vitamin D" compounds specifically, as Reinhold Vieth suggests, since they have completely different roles in the body - with calcitriol having one hormonal function and multiple functions as an intracrine and paracrine agent. These signaling systems need to be explained properly, since all health professionals need to understand them, and since they are currently almost entirely unknown, even to immunologists.
Such a Protocol would enable all the other FLCCC Protocols to be focused on their particular fields of concern, with additional discussion, references and guidance on the three "vitamin D" compounds, without the need to repeat all the guidance and other information in the main Vitamin D3 Supplementation Protocol.
Here are some "vitamin D" related shortcomings which I perceive in the current Protocols and other FLCCC guidance documents.
https://covid19criticalcare.com/tools-and-guides/all-about-vitamin-d3/ . The listed foods cannot contribute more than a small fraction of the vitamin D3 we need to be healthy. Many people over-estimate how much vitamin D3 they obtain from food or being outdoors. The 5000 IU a day general guidance in this document is about right for average weight adults, but Prof Wimalawansa's recommendations are better and apply to people of all ages, body weights and body morphologies - from the frail and underweight to those suffering from obesity.
The Sepsis Protocol https://covid19criticalcare.com/protocol/sepsis-care/ doesn't mention vitamin D. Sepsis patients are fighting for their lives hour-to-hour and almost invariably have terribly low 25-hydroxyvitamin D levels. They urgently need their level boosted safely over 50 ng/mL. Prof. Wimalawansa's 0.014 mg calcifediol per kg body weight treatment is the only way this can be done fast enough: in 4 hours or less. The MATH+ protocol https://covid19criticalcare.com/protocol/math-covid-hospital-treatment/ cites Prof. Wimalawansa's articles and states, correctly, that "calcifediol is particularly useful in acute infections like COVID-19, and in sepsis.".
The Cancer Care monograph https://covid19criticalcare.com/reviews-and-monographs/cancer-care/ does not explain that the immune system's reliance on 50 ng/mL or more circulating 25-hydroxyvitamin D is due tothe need to properly supply supply its cells' 25-hydroxyvitamin D >> calcitriol intracrine and paracrine signaling functions.
Fig 8 on page 78 is misleading in that it depicts the very low level of hormonal calcitriol (1,25(OH)2D3) binding to "vitamin D receptor" (VDR, but really the "calcitriol receptor") located at or in the plasma membrane, with the bound complex altering gene transcription so the cell generates multiple compounds which are parts of the immune response to cancer cells. VDR molecules are located in throughout the cytosol, not in or near the plasma membrane. The very low level of hormonal calcitriol, as it diffuses into the cytosol, has no significant effect on the 25-hydroxyvitamin D >> calcitriol intracrine and paracrine signaling systems which are crucial to the immune system's ability to tackle cancer cells, and bacterial, viral and fungal pathogens.
This diagram will confirm in many readers their mistaken belief that vitamin D3 supplementation "boosts the immune system" (which is generally the case) by raising hormonal calcitriol levels, secondary to the supplementation boosting circulating 25-hydroxyvitamin D levels. Circulating (hormonal) calcitriol levels do rise modestly with increased 25-hydroxyvitamin D levels (Fig 1 b of Tang et al. 2016 https:// www.nature.com/articles/s41598-019-43462-6) but this is a general trend which is smaller than the individual scatter in these levels. This has no significant effect on immune cells, since these cells' intracrine and paracrine signaling systems use higher levels of intracellular calcitriol.
The real reason that vitamin D3 supplementation improves immune system performance in most people is that it provides, perhaps for the first time in the person's life, sufficient (50 ng/mL) circulating 25-hydroxyvitamin D for immune cells' intracrine and paracrine signaling systems to function properly, so enabling the cells to respond fully and rapidly to their changing circumstances.
The Cancer Care monograph does not mention hypercalcemia of malignancy, which can occur - and be a serious problem - in several types of cancer. Tumor-adjacent macrophages fall into a pattern of hydroxylating 25-hydroxyvitamin D to calcitriol, for no good purpose, to such an extent that the intracellularly produced-calcitriol diffuses into the bloodstream in sufficiently large quantities to raise hormonal calcitriol levels well above the level that the kidneys are trying to maintain. (Hewison et al. 2009 https://doi.org/10.1359/jbmr.2003.18.3.579.)
This is a similar process to that in granulomatous disorders, such as sarcoidosis, in which macrophages and other immune cells form dysfunctional clusters, with the macrophages likewise producing sufficient calcitriol to disturb calcium-phosphate-bone metabolism. In both cases (this is my suggestion - I haven't seen it in the peer-reviewed literature) it is reasonable to suspect that this involves localised depletion of 25-hydroxyvitamin D which causes failures in proper immune responses, such as by causing Th1 regulatory lymphocytes to be unable to transition to their anti-inflammatory shutdown program after detecting the signal to do so. (Chauss et al. https://www.nature.com/articles/s41590-021-01080-3 and https://vitamindstopscovid.info/00-evi/#chauss).
The conventional view of sarcoidosis is that 25-hydroxyvitamin D levels should be minimised to reduce this pathological production of calcitriol. However, However, Kamphius et al. 2014 report that sarcoidosis patients do better with supplemental vitamin D3 and calcium: https://5nn.info/private/dp/1-protocol/#Kamphius-2014.
Perhaps boosting 25-hydroxyvitamin D levels - would also be the best approach with hypercalcemia in malignancy. If so, this would be due to it improving the immune system's ability to regulate itself, including the dysfunctional macrophages. This question requires careful consideration from oncologists such as Prof. Dalgliesh.
I think the Cancer Care monograph should cite and discuss the conventional protocols for dealing with this problem, including https://doi.org/10.2147/TCRM.S83681, https://doi.org/10.1210/er.2016-1070 and especially the 2023 "Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline" https://doi.org/10.1210/clinem/dgac621. These do not necessarily recommend reducing 25-hydroxyvitamin D levels and they are mainly concerned with drugs to counteract the elevated calcium ion levels. However, the authors of these articles were generally working with patients with much lower 25-hydroxyvitamin D levels than the 50+ ng/mL levels which are needed for proper immune responses to cancer cells, which the Cancer Care recommendations rightly seek to attain.
I suggest that The FLCCC Alliance allocates resources to apply for these 18 alternative therapies to be approved as cancer treatment drugs (for new indications). According to U.S. regulations, a new indication for a known drug can receive a three-year market exclusivity period. For example, if ivermectin is approved for a new cancer indication, this exclusivity could generate at least $10 billion in revenue over three years. If The FLCCC Alliance chooses not to pursue this, I would like to know why.
You missed IP-6, which caused my bladder tumors to bleed alerting my doctors to bladder cancer in stage 1. I feel it also assisted in my BCG treatments that halted the cancer for 10 years. I have just received successful BCG + IP-6 treatments halting the aggressive return of the bladder cancer still in stage 1. I am an active 86 YO woman that follows most of your protocols. Thank you FLCCC.
Extended fasting is missing from the list. We need practitioners who can support this.
True North Heath Center in Santa Rosa CA does this. 30 years experience in supervising fasters and research. Not cheap though.
Yes. I saw in the documentary.
I’ve done 4, 5 day fasts this year. I’d like to do 40 days, but I’d prefer to have a supportive doctor.
I just finished a 7-day fast. My longest is 14 days. My personal opinion is that if you have been able to complete 5 days without major complications AND you have the discipline to break your fast slowly over 1/2 the time you were fasting, then you can probably gradually increase on your own safely (500 cal is the limit for day 1 re-feeding - read-up on Refeeding Syndrome). 40 days is going to require a great deal of care in breaking the fast and if you gradually build-up to longer fasts, you might not have the fat reserves to do 40 days anyway - you lose 3/4 pound per day of fat.
Yes, I have phosphorus ready for re-feeding. Thanks for your input. I’ve learned how much sodium (and potassium and magnesium) that my body needs on a 5 day one. I’m aware of the need to add calcium, etc. after 14 days. Congrats on your 14 day fast. Was that your goal?
Yes. If you plan on going further than 14 days, I found that after 14 days I felt like I could go indefinitely and have OK energy - so that's something you can look forward to if you want to go for it. I think it starts to get slowly better after 7 days. For the 14 day fast I took vacation for the first 7 days and very light work for the next 7.
Would either of you be willing to share the best material you have on reading up on this? I feel I always encounter so much contradictory material (probably intentionally like with diet) that it becomes difficult to parse. So I’d like to really understand the mechanics and the differences between the different types and lengths.
I will pass this on to anyone I think will read it. Lots of people getting cancer these days… 🧐 Lots of people still in denial as to why.
More life saving investigation and publication. Thank you!
https://www.facebook.com/share/v/iv5YfSAb3KTF2MZV/?mibextid=UalRPS. John Campbell re Ivermectin for cancer.
(1 of 2) The most important single piece of nutrition advice is to supplement vitamin D3 to attain at least the 50 ng/mL (125 nmol/L = 1 part in 20,000,000 by mass) level of 25-hydroxyvitamin D (as measured in "vitamin D" blood tests), which the immune system needs to function properly.
Links to and discussion of the most pertinent research on the three vitamin D compounds and the immune system are at: https://vitamindstopscovid.info/00-evi/. This begins with recommendations from New Jersey based Professor of Medicine Sunil Wimalawansa for how much vitamin D3 to supplement to attain this level safely, without the need for blood tests or medical monitoring. The amount depends on body weight and obesity status. For 70 kg 154lb body weight without obesity, 0.125 milligrams (125 micrograms = 5000 IU) a day is a good amount. These recommendations are based on his 2022 article in Nutrients: http:// www.mdpi.com/2072-6643/14/14/2997 as simplified somewhat in his FLCCC webinar: https:// odysee.com/@FrontlineCovid19CriticalCareAlliance:c/ Weeekly_Webinar_Aug16_2023:d?t=3386.
These supplemental intake quantities are 5 or more times those recommended by governments and many doctors, who are only aiming to attain the 20 ng/mL (50 nmol/L) level of circulating 25-hydroxyvitamin which the kidneys need to perform their role in the regulation of calcium-phosphate-bone metabolism.
The fuller version of this article: https://covid19criticalcare.com/alternative-cancer-treatments-interventions/ states this, and nominates 55 to 90 ng/mL (137 to 225 nmol/L) circulating 25-hydroxyvitamin D as the target range. This is healthy for the vast majority of people, who without proper vitamin D3 supplementation, or substantial ultraviolet-B radiation of ideally white skin, typically have levels between 5 and 25 ng/mL.
The research literature indicates that 25-hydroxyvitamin D levels up to 375 nmol/L (150 ng/mL) do not lead to hypercalcemia - an excessive level of calcium ions in the bloodstream, with reduced calcium in the bone. (Endocrine Society Clinical Practice Guideline 2011: https://doi.org/10.1210/jc.2011-0385 and McCullough et al. 2019: https://sci-hub.se/10.1016/j.jsbmb.2018.12.010.)
However, there is a report that some people suffer ill effects with 25-hydroxyvitamin D levels such as 197 nmol/L (79 ng/mL), such as after several years of supplementing what for most average weight adults is a perfectly healthy amount of vitamin D3 - 125 micrograms (5000 IU) a day: https://www.devaboone.com/ post/vitamin-d-part-2-shannon-s-story. These must be quite rare, since I have not seen such an account in the peer-reviewed literature.
Compared to the current situation of almost ubiquitous, unsupplemented, levels of 25-hydroxyvitamin D being a fraction of what the immune system needs to function properly, if everyone attained at least 50 ng/mL, there would be far less incidence of cancer or infectious diseases caused by bacteria and viruses. In the case of infectious diseases, such as COVID-19, influenza etc. fully functioning immune systems not only reduce the chance of severe symptoms, but reduce the number of bacteria or virus particles shed, which greatly reduces the rate at which the disease can be transmitted through a population.
The fuller version of this article https://covid19criticalcare.com/alternative-cancer-treatments-interventions/ states that vitamin D3 "is a hormone". This is a common mistake, as is the practice in medicine and research of referring to all three (broadly) "vitamin D" compounds as "vitamin D", as if they were effectively the same thing. This was pointed out by Prof Reinhold Vieth in 2004: https://sci-hub.se/10.1016/j.jsbmb.2004.03.037.
The first compound, vitamin D3 cholecalciferol is for most practical purposes a vitamin. While we can produce it from UV-B skin exposure, most people cannot access the required amount of UV-B except from high elevation direct sunshine (without intervening glass, clothing or sunscreen) on cloud-free summer days, or at any time of the year except monsoon in equatorial regions. UV-B skin exposure damages DNA and so raises the risk of skin cancer. Furthermore, it has been proposed https://journals.physiology.org/doi/full/10.1152/ajpregu.00136.2019 that UV-B exposure degrades folate. This means that ingesting vitamin D3 is essential for most people to be healthy, making it a vitamin.
The second compound, 25-hydroxyvitamin D calcifediol (also: "calcidiol") is made primarily in the liver by hydroxylating vitamin D3 at the 25th carbon. About 1/4 of ingested or skin-produced vitamin D3 goes into circulation as 25-hydroxyvitamin D, where it has a half life of weeks to months (after long-term vitamin D3 supplementation).
Neither vitamin D3 nor 25-hydroxyvitamin D function as hormones. They are not signaling molecules. A hormone is a long-distance blood-borne signalling molecule: it is made somewhere in the body and goes into circulation in the bloodstream (and potentially the cerebrospinal fluid) where its level (concentration) affects or controls the behaviour of cells of one or more types in all parts of the body.
As Reinhold Vieth pointed out, referring to vitamin D3 as a hormone is not only incorrect, but will make many people overly wary of supplementing this vital nutrient. This is especially so when the small amounts required on average per day, (125 micrograms, totalling a gram every 22 years) are referred to with such large numbers as "5000 International Units".
The third compound is 1,25-dihydroxyvitamin D calcitriol, made from 25-hydroxyvitamin D by hydroxylating it (replacing a hydrogen with an oxygen-hydrogen hydroxyl group) on the number 1 carbon. Calcitriol has one well known hormonal function, so many people consider it to be a hormone. They are not aware that it also has many non-hormonal functions. As part of a feedback network involving the parathyroid gland and osteocyte bone cells, the kidneys maintain a very low (ca. 0.05 ng/mL), generally stable, level of circulating calcitriol, which acts as a long-distance blood-borne (endocrine) signaling molecule, hormonally affecting several types of cell which are involved in calcium and phosphate absorption and excretion, and bone maintenance.
Although structurally related, these three compounds have entirely different roles in the body, so it is a mistake to refer to them all as "vitamin D".
The immune system is not significantly affected by this very low, stable, level of circulating, hormonal calcitriol. Many types of immune cell rely on a good circulating level of 25-hydroxyvitamin D to supply their intracrine (inside each cell) and paracrine (to nearby cells of different types) signalling systems, which are crucial to each cell's ability to respond to its changing circumstances. These two signaling systems have never been explained in a tutorial fashion in the peer-reviewed literature. For such an explanation, see: https://vitamindstopscovid.info/00-evi/#02-compounds or in greater detail: https://vitamindstopscovid.info/02-intracrine/.
Fabulous! Thank you.
You might want to study the mechanism of ClO2 (remember, the much maligned "bleach"). It may have application as a pro-oxidant the immune system uses to attack cancer as well as many other diseases.
www.theuniversalantidote.com documentary.
Dr. Paul Marik has a unique talent for coming up with alternative treatments for disease by using common pharmaceuticals (vitamins/supplements) and drugs that are produced for different ailments. I think the combination of Ivermectin and Fenbendazole is particularly effective as a cancer treatment.
If anyone knows if fasting truly works as an alternative to chemo please fill me in. My fiance, who is only 33 has metastatic breast cancer in her bones and now beginning in her lungs. We will try anything. Thanks.
Hello Jon:
The FLCCC Alliance does not provide medical advice or consultation, but treatment of turbo cancer was a panel discussion at our conference earlier this year. I hope this helps. https://covid19criticalcare.com/emergence-and-treatment-of-turbo-cancers/
Hello FLCCC Alliance!
Dr. Bryan Ardis, in his book released the last week in September of 2024, "Moving Beyond the COVID-19 Lies: Restoring Health & Hope For Humanity", fully documents that Snake Venom (from the King Cobra snake, the Chinese Krait snake, and others) was put into all the C-19 vaccines.
He also documents how Snake Venom causes miscarriages, infertility, turbo cancers, myocarditis, sudden death, heart attacks, blood clotting, Long Covid, mental health issues, and more.
Additionally, he cites a Harvard Study showing we all were lied to about Nicotine which is Not addictive. The addictive element in tobacco are the pyrazine chemicals. Nicotine is found in eggplant, potatoes, and more.
Wearing a Nicotine patch of 2 mg of 3 mg will eject the snake venom from the nicotinic receptor sites in the body where it 'lands' which will then get flushed out when using the restroom. Very few smokers got COVID-19 during the pandemic because of the nicotine found in the tobacco plant (to which pyrazines are added).
He also documents how wearing a Nicotine patch resolves all Long COVID issues.
At this late hour I can't locate in his book what he said nicotine did to turbo cancers except I remember it described a person with brain cancer whose tumor was reduced by 72% (or some huge figure like that) by using "the nutrient" nicotine.
Amazon sold out of his book on October 10th, I believe, and remains sold out. But you can order his book at www.thedrardisshow.com.
While you are there, watch his video on the first page, "The Explosive Truth, Origin, & Antidote for C-19". You will be nothing short of astounded.
Likewise for his 3-hour video on nicotine called "The Other N-Word-- the Complete 3 Hour Nicotine Expose". Lastly, his "Resources" section has plenty of information on nicotine and everything else.
This is Not a post advocating solely for Nicotine because his book lists many, and I do mean MANY remedies found in Nature for C-19 symptoms: Vitamin C, Glutathione, EDTA, and many more too numerous to list here. The last fourth of his book will put all his remedies from Nature in context in relation to specific symptoms.
So not only is Dr. Ardis's book solidly researched and documented, it also lists solutions for every COVID-19 issue.
Lastly, in one of his talks, he said Ozempic and Wegovy have snake venom in them. He also said to go to www.made-in-china.com and type in "snake venom peptides" into the search engine. When you do that, THOUSANDS of womens' cosmetics will come up each of which has some type of snake venom in them. Snake venom causes cancer and much more as listed above.
I can't do all his findings justice in this brief post. I encourage you to consider ordering the book. Keep up the great work you all do at FLCCC!
How devastating :-(
I've heard of folks having success with adjunctive supportive therapies like taking apricot kernel seeds, essiac tea, green tea, grape skins, a diet rich in cruciferous vegetables and mistletoe injections.
Cancer cells feed on glucose/sugar/carbs. Fasting gives the body time to take out the cellular trash. A keto very low carb diet can slow the cancer.
Try Ivermectin and Fenbendazole— Joe Tippins protocol
I believe fasting will help, along with a high protein/ low carb diet.
Good Luck
I recommend checking out Georgi Dinkov’s research on cancer & B vitamins + aspirin to treat cancer as metabolic disease and the problems of ketosis.
https://youtu.be/xXq4S2Dx_b8?si=BfL6kdBxUbt9mWAA
Vitamin B17 - why is that not on the list. Or what about Grape fasting and mono -fruit fasting.
If the metabolic theory of cancer is correct, fruit fasting is going to feed cancer because of the sugar content.
Vitamin-D3 supplementation is valuable for so much more than just cancer though deficiency is probably typical at the start of cancer.
Check out also
https://vitamindwiki.com/Cancer
https://vitamindstopscovid.info/
(2 of 2) There is very little vitamin D3 in food, including food which has been supplemented with vitamin D (often with the less effective vitamin D2). UV-B skin exposure can produce sufficient vitamin D3 to meet the needs of the immune system, but this is neither a practical nor safe way of attaining most of the vitamin D3 we need, year after year, due to sufficient UV-B light being generally unavailable and due to it damaging the skin, raising the risk of skin cancer and, as mentioned in my first comment, depleting folate.
So proper vitamin D3 supplementation, along the lines recommended by Prof. Wimalawansa (see previous comment, and some FLCCC protocols including MATH+) is essential for human health.
I suggest that the FLCCC develop a Vitamin D3 supplementation Protocol, to which all other protocols would refer.
This would begin with Prof. Wimalawansa's recommendations for long-term vitamin D3 supplementation, but also include his recommendations for using a single oral dose of 0.014 milligrams of calcifediol (which *is* 25-hydroxyvitamin D) per kilogram body weight (so 1 milligram for average weight adults) to boost the patient's 25-hydroxyvitamin D level from typical unsupplemented levels of 25 ng/mL or less, safely over 50 ng/mL, in 4 hours. This is also in the MATH+ protocol, along with a loading dose of ca. 10 mg (400,000 IU) vitamin D3, which takes about 4 days, due to the delays inherent in hydroxylation in the liver.
I suggest the protocol refer to the three (broadly) "vitamin D" compounds specifically, as Reinhold Vieth suggests, since they have completely different roles in the body - with calcitriol having one hormonal function and multiple functions as an intracrine and paracrine agent. These signaling systems need to be explained properly, since all health professionals need to understand them, and since they are currently almost entirely unknown, even to immunologists.
Such a Protocol would enable all the other FLCCC Protocols to be focused on their particular fields of concern, with additional discussion, references and guidance on the three "vitamin D" compounds, without the need to repeat all the guidance and other information in the main Vitamin D3 Supplementation Protocol.
Here are some "vitamin D" related shortcomings which I perceive in the current Protocols and other FLCCC guidance documents.
https://covid19criticalcare.com/tools-and-guides/all-about-vitamin-d3/ . The listed foods cannot contribute more than a small fraction of the vitamin D3 we need to be healthy. Many people over-estimate how much vitamin D3 they obtain from food or being outdoors. The 5000 IU a day general guidance in this document is about right for average weight adults, but Prof Wimalawansa's recommendations are better and apply to people of all ages, body weights and body morphologies - from the frail and underweight to those suffering from obesity.
The Sepsis Protocol https://covid19criticalcare.com/protocol/sepsis-care/ doesn't mention vitamin D. Sepsis patients are fighting for their lives hour-to-hour and almost invariably have terribly low 25-hydroxyvitamin D levels. They urgently need their level boosted safely over 50 ng/mL. Prof. Wimalawansa's 0.014 mg calcifediol per kg body weight treatment is the only way this can be done fast enough: in 4 hours or less. The MATH+ protocol https://covid19criticalcare.com/protocol/math-covid-hospital-treatment/ cites Prof. Wimalawansa's articles and states, correctly, that "calcifediol is particularly useful in acute infections like COVID-19, and in sepsis.".
The Cancer Care monograph https://covid19criticalcare.com/reviews-and-monographs/cancer-care/ does not explain that the immune system's reliance on 50 ng/mL or more circulating 25-hydroxyvitamin D is due tothe need to properly supply supply its cells' 25-hydroxyvitamin D >> calcitriol intracrine and paracrine signaling functions.
Fig 8 on page 78 is misleading in that it depicts the very low level of hormonal calcitriol (1,25(OH)2D3) binding to "vitamin D receptor" (VDR, but really the "calcitriol receptor") located at or in the plasma membrane, with the bound complex altering gene transcription so the cell generates multiple compounds which are parts of the immune response to cancer cells. VDR molecules are located in throughout the cytosol, not in or near the plasma membrane. The very low level of hormonal calcitriol, as it diffuses into the cytosol, has no significant effect on the 25-hydroxyvitamin D >> calcitriol intracrine and paracrine signaling systems which are crucial to the immune system's ability to tackle cancer cells, and bacterial, viral and fungal pathogens.
This diagram will confirm in many readers their mistaken belief that vitamin D3 supplementation "boosts the immune system" (which is generally the case) by raising hormonal calcitriol levels, secondary to the supplementation boosting circulating 25-hydroxyvitamin D levels. Circulating (hormonal) calcitriol levels do rise modestly with increased 25-hydroxyvitamin D levels (Fig 1 b of Tang et al. 2016 https:// www.nature.com/articles/s41598-019-43462-6) but this is a general trend which is smaller than the individual scatter in these levels. This has no significant effect on immune cells, since these cells' intracrine and paracrine signaling systems use higher levels of intracellular calcitriol.
The real reason that vitamin D3 supplementation improves immune system performance in most people is that it provides, perhaps for the first time in the person's life, sufficient (50 ng/mL) circulating 25-hydroxyvitamin D for immune cells' intracrine and paracrine signaling systems to function properly, so enabling the cells to respond fully and rapidly to their changing circumstances.
The Cancer Care monograph does not mention hypercalcemia of malignancy, which can occur - and be a serious problem - in several types of cancer. Tumor-adjacent macrophages fall into a pattern of hydroxylating 25-hydroxyvitamin D to calcitriol, for no good purpose, to such an extent that the intracellularly produced-calcitriol diffuses into the bloodstream in sufficiently large quantities to raise hormonal calcitriol levels well above the level that the kidneys are trying to maintain. (Hewison et al. 2009 https://doi.org/10.1359/jbmr.2003.18.3.579.)
This is a similar process to that in granulomatous disorders, such as sarcoidosis, in which macrophages and other immune cells form dysfunctional clusters, with the macrophages likewise producing sufficient calcitriol to disturb calcium-phosphate-bone metabolism. In both cases (this is my suggestion - I haven't seen it in the peer-reviewed literature) it is reasonable to suspect that this involves localised depletion of 25-hydroxyvitamin D which causes failures in proper immune responses, such as by causing Th1 regulatory lymphocytes to be unable to transition to their anti-inflammatory shutdown program after detecting the signal to do so. (Chauss et al. https://www.nature.com/articles/s41590-021-01080-3 and https://vitamindstopscovid.info/00-evi/#chauss).
The conventional view of sarcoidosis is that 25-hydroxyvitamin D levels should be minimised to reduce this pathological production of calcitriol. However, However, Kamphius et al. 2014 report that sarcoidosis patients do better with supplemental vitamin D3 and calcium: https://5nn.info/private/dp/1-protocol/#Kamphius-2014.
Perhaps boosting 25-hydroxyvitamin D levels - would also be the best approach with hypercalcemia in malignancy. If so, this would be due to it improving the immune system's ability to regulate itself, including the dysfunctional macrophages. This question requires careful consideration from oncologists such as Prof. Dalgliesh.
I think the Cancer Care monograph should cite and discuss the conventional protocols for dealing with this problem, including https://doi.org/10.2147/TCRM.S83681, https://doi.org/10.1210/er.2016-1070 and especially the 2023 "Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline" https://doi.org/10.1210/clinem/dgac621. These do not necessarily recommend reducing 25-hydroxyvitamin D levels and they are mainly concerned with drugs to counteract the elevated calcium ion levels. However, the authors of these articles were generally working with patients with much lower 25-hydroxyvitamin D levels than the 50+ ng/mL levels which are needed for proper immune responses to cancer cells, which the Cancer Care recommendations rightly seek to attain.
I suggest that The FLCCC Alliance allocates resources to apply for these 18 alternative therapies to be approved as cancer treatment drugs (for new indications). According to U.S. regulations, a new indication for a known drug can receive a three-year market exclusivity period. For example, if ivermectin is approved for a new cancer indication, this exclusivity could generate at least $10 billion in revenue over three years. If The FLCCC Alliance chooses not to pursue this, I would like to know why.
Thank you Xuewu. I have forwarded your suggestion to the FLCCC executive team.
You missed IP-6, which caused my bladder tumors to bleed alerting my doctors to bladder cancer in stage 1. I feel it also assisted in my BCG treatments that halted the cancer for 10 years. I have just received successful BCG + IP-6 treatments halting the aggressive return of the bladder cancer still in stage 1. I am an active 86 YO woman that follows most of your protocols. Thank you FLCCC.
Purchased the first edition - is the second addition different or have additional information? Amazon does not have the Second Edition - thank you